Vikings RB Dalvin Cook inactive for second time in three weeks; Trae Waynes sits

Jeff Hanisch, USA TODAY Sports Images

Cook's hamstring injury keeps him out again; Waynes will miss game with a concussion

Dalvin Cook's troublesome season for the Minnesota Vikings continues on Sunday as the second-year running back is inactive for the second time in three weeks because of a lingering hamstring injury.

Cook returned last week and got 10 carries while being on limited snaps, but the hamstring injury continues to bother Cook in his comeback season from last year's knee surgery. Through the first five weeks, Cook has been inactive twice and has a total of 36 carries.

Minnesota is also without starting cornerback Trae Waynes on Sunday at Philadelphia because of a concussion. The Vikings inactive list includes quarterback Kyle Sloter, cornerback Marcus Sherels, linebacker Devante Downs and defensive ends Tashawn Bower and Everson Griffen.

Griffen will miss his third straight game as he deals with his mental health and there is no timeline for his return to the team.

Sherels is dealing with a injury to his ribs and Bower has an ankle injury.

Without Bower and Griffen, the Vikings activated rookie defensive tackle Jalyn Holmes for the first time this season. Defensive tackle Tom Johnson (ankle) returns after missing last week's loss to the Los Angeles Rams.