Mackensie Alexander held out of practice; Vikings-49ers injury report

Jeff Hanisch, USA TODAY Sports Images

Pat Elflein, Riley Reiff, Xavier Rhodes and Marcus Sherels were limited for Vikings on Wednesday

EAGAN, Minn -- Mackensie Alexander, expected to be the Minnesota Vikings' No. 1 nickel back this season was held out of practice on Wednesday, along with backup running back Roc Thomas.

The Minnesota Vikings released their first injury report ahead of the Week One game on Sunday against the San Francisco 49ers. Alexander is sidelined with an ankle injury. He was seen running on a side field with the team's athletic trainers in the portion of practice open to media. Thomas is also dealing with an ankle injury.

Center Pat Elflein (ankle/shoulder), left tackle Riley Reiff (foot), cornerback Xavier Rhodes (hamstring) and returner/cornerback Marcus Sherels (hamstring) were limited in Wednesday's practice. Receiver Stacy Coley (groin) was listed as a full participant.

Elflein is still working his way back from ankle and shoulder surgeries during the offseason. He's practicing for the first time this week since the starting of training camp after being activated off the physically unable-to-perform list. Brett Jones is expected to start at center against San Francisco on Sunday.

Sherels had been held out since injuring his hamstring in the third preseason game.

Rookie Mike Hughes, who had missed some recent practices, practiced and wasn't listed on the injury report.

The 49ers listed starting linebacker Malcolm Smith limited with a hamstring injury. Offensive tackle Garry Gilliam (concussion) and safety Jimmie Ward (quadriceps) were also limited. Offensive lineman Erik Magnuson didn't practice with a hamstring injury.